You have to fly into Bangkok, and then take a bus to Sangkhlaburi that leave daily.
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How to Reach Sangkhlaburi from India
Many airlines like Jet, Indigo, Air Asia, Air India fly from major cities in India like Mumbai, Banglore, Delhi, Ahemdabad, etc. to Bangkok.
How to reach Sangkhlaburi by flight
You have to fly to the Suvarnabhumi International Airport of Bangkok from your respective country, and then take the bus to Sangkhlaburi.
How to reach Sangkhlaburi by road
Minivan services from Bangkok depart from the Morchit stand costing around 2,000 Baht. This can prove to be very expensive and uncomfortable too.
How to reach Sangkhlaburi by bus
Direct buses leave daily to and from Morchit station of Bangkok. The trip takes around 7-8 hours and costs 250 Baht. To avoid this long journey, most travellers prefer to halt at Kanchanaburi. Buses from Kanchanaburi to Sangkhlaburi will take around 4 hours and cost around 150 Baht.
Local transport in Sangkhlaburi
The most common way to get around Sangkhlaburi is motorcycle taxi. It is available easily and costs between 20-50 Baht depending on the distance. Songthaews and buses are other cheaper options. However, walking is the most pleasant option that can give you a very notable experience. Some guesthouses have motorbike and bicycle renting services too.