After arriving at the Cancun Airport, you can take a bus to reach Playa, where the bus stops at 5th Avenue and Juarez. If you're coming from Cozumel, you'll have to ride in a ferry to reach the city.
There are a number of airlines which offer connecting flights for Indians to reach Cancun Airport.
Cancun International Airport is the nearest airport, approx. 1 hour drive to Playa Del Carmen. Alternatively, you can land at Cozumel International Airport and then take a ferry to reach Playa.
Cabs are available to commute to nearby cities. Renting a car might not be the best option to travel around.
There are bus terminals at La Quinta and Juarez which connect to nearby towns and areas.
Ferries to Cozumel are available from 6 am to 11 pm.
The best way to navigate the beach town is on foot. Taxis can be hired to move around, just remember to negotiate with the prices before getting in. Although rental cars are available, but they only make sense if you want to visit some places outside the city.